Dr. Nashat Latib

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FERTILITY

The Impact of Weight or Body Mass on Fertility

By Dr. Nashat Latib • July 25, 2023

How Functional Medicine Can Help Intervene Naturally

When it comes to fertility, many factors come into play, including age, hormonal balance, lifestyle choices, and overall health. Among these factors, weight or body mass index (BMI) can significantly impact a person’s ability to conceive. Both underweight and overweight conditions can disrupt hormonal balance, menstrual cycles, and overall reproductive health. However, with the help of functional medicine, natural interventions can be implemented to restore fertility and improve the chances of successful conception. In this article, we will explore the impacts of weight or BMI on fertility and delve into the ways functional medicine can help address these concerns holistically.

The Link between Weight/BMI and Fertility

Underweight and Fertility

Being underweight, defined as having a BMI below the normal range (18.5), can affect fertility in various ways. Insufficient body fat can lead to irregular or absent menstrual cycles due to hormonal imbalances. Additionally, low body weight can disrupt the production of reproductive hormones like estrogen, progesterone, and luteinizing hormone (LH), which are crucial for ovulation and implantation.

Underweight women may experience hormonal imbalances, disrupted menstrual cycles, and irregular ovulation, which can significantly affect their ability to conceive. In some cases, extreme underweight conditions, such as those associated with eating disorders like anorexia nervosa, can cause amenorrhea (absence of menstrual periods) and severely impair fertility.

Overweight and Fertility

On the other end of the spectrum, being overweight or obese (BMI above 25) can also pose fertility challenges. Excessive body weight can disrupt hormonal balance, leading to conditions like polycystic ovary syndrome (PCOS), which is a common cause of infertility. Moreover, excess body fat produces estrogen, leading to an imbalance with other reproductive hormones and interfering with ovulation and implantation.

When it comes to understanding how excess weight can affect fertility in women, it’s important to explore the underlying science behind this connection. Several mechanisms contribute to the challenges faced by overweight women when trying to conceive. Here are the key scientific factors involved:

  1. Hormonal Imbalances: Adipose tissue, or body fat, produces estrogen, a hormone involved in regulating the menstrual cycle and ovulation. In overweight women, the excess body fat leads to higher levels of estrogen, which can disrupt the delicate balance of other reproductive hormones such as progesterone and luteinizing hormone (LH). This hormonal imbalance can interfere with regular ovulation, making it more difficult to conceive.
  2. Insulin Resistance and PCOS: Overweight women are more prone to developing insulin resistance, a condition in which the body’s cells become less responsive to insulin. Insulin resistance can contribute to the development of polycystic ovary syndrome (PCOS), a hormonal disorder that affects ovulation. PCOS is a leading cause of infertility in women and is characterized by cysts on the ovaries, irregular menstrual cycles, and high levels of male hormones (androgens). The combination of insulin resistance and PCOS can further complicate fertility by inhibiting ovulation and disrupting the menstrual cycle.
  3. Inflammation: Excess weight is associated with chronic low-grade inflammation in the body. This inflammation can disrupt the normal physiological processes involved in conception. It can affect the function of the ovaries, disrupt the growth and development of the egg, and impair implantation of the fertilized egg in the uterus.
  4. Reduced Egg Quality: Studies have shown that excess weight can negatively impact egg quality. The quality of eggs declines with age, but overweight or obese women may experience a further decline in egg quality due to the inflammatory environment associated with excess weight. Poor egg quality can reduce the chances of successful fertilization and implantation, leading to difficulties in getting pregnant.
  5. Increased Risk of Pregnancy Complications: Overweight women who do become pregnant may face an increased risk of pregnancy complications such as gestational diabetes, preeclampsia, and preterm birth. These complications can further affect fertility by impacting the health of the mother and the developing fetus.
If you would like our support to walk through the process step by step, we are here for you! Watch our free, on-demand masterclass here and take the action step to apply to work with us. We’ve helped countless couples like you succeed in optimizing their fertility, even when they are starting a family a little later in life.

Overweight and Fertility in Men

Believe it or not, it’s true that being overweight can also affect fertility in men. Excess weight can have various negative impacts on male reproductive health and fertility. Some ways in which being overweight can affect male fertility include:

  • Hormonal Imbalances: Similar to women, excess weight in men can lead to hormonal imbalances. Adipose tissue produces estrogen, and higher levels of body fat can result in increased conversion of testosterone (the primary male sex hormone) into estrogen through an enzyme called aromatase. This imbalance between estrogen and testosterone can disrupt sperm production and quality.
  • Reduced Sperm Quality: Obesity has been associated with poor sperm quality, including decreased sperm concentration, motility (movement), and morphology (shape). Studies have shown that overweight and obese men tend to have lower sperm counts and a higher percentage of abnormal sperm compared to men with a healthy weight. These factors can impair the ability of sperm to reach and fertilize an egg.
  • Erectile Dysfunction: Obesity is a risk factor for erectile dysfunction (ED). The excess weight can contribute to vascular problems and impair blood flow, leading to difficulties in achieving or maintaining an erection. Erectile dysfunction can impact sexual intercourse and the ability to conceive naturally.
  • Increased Inflammation: Obesity is associated with chronic low-grade inflammation throughout the body, including the reproductive system. Inflammation can impair sperm production, function, and overall fertility.
  • DNA Fragmentation: Research suggests that overweight and obese men may have higher levels of DNA fragmentation in their sperm. DNA fragmentation refers to abnormalities or breaks in the DNA strands of sperm. Increased DNA fragmentation can affect the sperm’s ability to fertilize an egg properly and can also lead to an increased risk of miscarriages and genetic abnormalities in offspring.
  • Impact on Assisted Reproductive Technologies (ART): Couples who have sought assisted reproductive technologies such as in vitro fertilization (IVF), may experience reduced success rates as a result of an overweight male partner. Studies have shown that overweight or obese men have lower fertilization rates and lower implantation rates during IVF procedures compared to men with a healthy weight.

It’s important to note that weight and overall health are interconnected, and addressing lifestyle factors such as diet, exercise, and stress management can positively impact both weight and fertility. Achieving a healthy weight, whether underweight or overweight, is crucial for optimizing fertility and increasing the chances of successful conception. Furthermore, by understanding the scientific mechanisms at play, individuals can make informed decisions about their health and seek appropriate interventions to address weight-related fertility issues. 

Functional Medicine Approach to Fertility

In our line of work, we use Functional Medicine as a holistic approach to address the underlying causes of health issues rather than merely treating the symptoms with invasive procedures or complex medications. When it comes to fertility and weight/BMI concerns, Dr. Christina and I offer several interventions in our unique 4R Fertility Formula™ to restore balance and optimize reproductive health naturally:

  • Education and Awareness: All couples in our program are educated with the most recent scientific knowledge of fertility and how to optimize it. You learn about nutrient-dense foods, portion control, macronutrients, and the impact of different food choices on your body. Increasing your awareness of the nutritional value of foods can help you make informed decisions and develop healthier eating habits.
  • Nutritional Support: We review your labs and assess your nutritional status in order to design a personalized plan to optimize fertility. For underweight individuals, a nutrient-dense diet that includes adequate healthy fats, proteins, and complex carbohydrates is crucial for restoring hormonal balance and supporting reproductive functions. In the case of overweight individuals, a nutrition plan aimed at achieving a healthy weight and reducing inflammation can be beneficial.
  • Hormonal Balance: Functional medicine aims to restore hormonal balance by addressing the root causes of imbalances. Once we identify hormonal deficiencies or excesses, we create a tailored treatment plan. This may include lifestyle modifications, targeted supplementation, and stress reduction techniques to support the endocrine system and enhance fertility.
  • Managing Inflammation: Inflammation is often associated with weight gain and hormonal imbalances. Our work addresses underlying inflammation by identifying potential triggers such as food sensitivities, gut health issues, or environmental toxins. By reducing inflammation, the body’s overall function improves, positively impacting fertility.
  • Behavior and Habit Change: Successful weight loss involves changing behaviors and adopting healthier habits, as well as identifying and addressing any unhealthy eating patterns or emotional triggers that may contribute to overeating or poor food choices. Our team of professionals know how to help you make lasting changes to your lifestyle. You only need to be motivated to be changed in the first place!
  • Stress Management: Chronic stress can have a significant impact on fertility by disrupting hormone production and ovulation. Included in our program are stress reduction techniques like mindfulness, meditation, and other mind-body practices. By addressing stressors and supporting the body’s stress response system, functional medicine helps optimize reproductive health.
  • A Personalized Approach: We know that every individual and couple is unique, and what works for one may not work for another. Consulting with a registered dietitian, nutritionist, we can help you tailor a nutrition plan specific to your needs and goals. We can take into account your current health status, dietary preferences, and any underlying health conditions to create a personalized approach that optimizes weight loss and overall well-being.

Adopting a functional nutritional lifestyle to lose weight can be challenging but is certainly achievable with the right approach and mindset. The difficulty may vary depending on individual factors such as current habits, motivation, support systems, and personal circumstances. However, we are here to offer support and accountability. With a support system, you and your partner can greatly enhance your chances of success. 

Conclusion

Weight or BMI plays a crucial role in fertility, affecting both underweight and overweight individuals. However, with the help of functional medicine, natural interventions can be implemented to address these concerns and restore reproductive health holistically. By focusing on personalized nutrition, hormonal balance, inflammation management, and stress reduction, functional medicine offers a comprehensive approach to enhance fertility naturally. If you’re struggling with weight-related fertility issues, consider our functional medicine program in your journey to pregnancy. Click here to watch our on-demand webinar, where we reveal the 4R Fertility FormulaTM we use to work with our clients. If what we share sounds good, we invite you to apply for a spot in our high-touch, individualized group program that has over an 80% success rate in helping couples conceive naturally. We are dedicated to providing our clients with the support and tools necessary to optimize their chances of conception and build a healthy future family.

References

  1. Sepidarkish M, Maleki-Hajiagha A, Maroufizadeh S, Rezaeinejad M, Almasi-Hashiani A, Razavi M. The effect of body mass index on sperm DNA fragmentation: a systematic review and meta-analysis. Int J Obes (Lond). 2020 Mar;44(3):549-558. doi: 10.1038/s41366-020-0524-8. Epub 2020 Jan 16. PMID: 31949297.
  2. Dupont C, Faure C, Sermondade N, Boubaya M, Eustache F, Clément P, Briot P, Berthaut I, Levy V, Cedrin-Durnerin I, Benzacken B, Chavatte-Palmer P, Levy R. Obesity leads to higher risk of sperm DNA damage in infertile patients. Asian J Androl. 2013 Sep;15(5):622-5. doi: 10.1038/aja.2013.65. Epub 2013 Jun 24. PMID: 23792341; PMCID: PMC3881654.
  3. Pearce KL, Hill A, Tremellen KP. Obesity related metabolic endotoxemia is associated with oxidative stress and impaired sperm DNA integrity. Basic Clin Androl. 2019 May 13;29:6. doi: 10.1186/s12610-019-0087-5. PMID: 31114691; PMCID: PMC6513521.
  4. Dağ ZÖ, Dilbaz B. Impact of obesity on infertility in women. J Turk Ger Gynecol Assoc. 2015 Jun 1;16(2):111-7. doi: 10.5152/jtgga.2015.15232. PMID: 26097395; PMCID: PMC4456969.
  5. Hunter E, Avenell A, Maheshwari A, Stadler G, Best D. The effectiveness of weight-loss lifestyle interventions for improving fertility in women and men with overweight or obesity and infertility: A systematic review update of evidence from randomized controlled trials. Obes Rev. 2021 Dec;22(12):e13325. doi: 10.1111/obr.13325. Epub 2021 Aug 13. PMID: 34390109.
  6. Best D, Bhattacharya S. Obesity and fertility. Horm Mol Biol Clin Investig. 2015 Oct;24(1):5-10. doi: 10.1515/hmbci-2015-0023. PMID: 26351959.
  7. Amiri M, Ramezani Tehrani F. Potential Adverse Effects of Female and Male Obesity on Fertility: A Narrative Review. Int J Endocrinol Metab. 2020 Sep 28;18(3):e101776. doi: 10.5812/ijem.101776. PMID: 33257906; PMCID: PMC7695350.